Find the right
WGS or DNA test

The most recognized name in consumer DNA testing. 23andMe offers health predisposition reports (including BRCA1/BRCA2), carrier status screening, and ancestry composition across 2,000+ geographic regions. Their FDA-authorized health reports set them apart from most competitors.

The largest consumer DNA database with over 25 million users. AncestryDNA specializes in ethnicity estimates and family tree building with access to billions of historical records. Their Traits add-on provides basic wellness and appearance insights, but they do not offer health risk reports.

A strong alternative to AncestryDNA with a particularly large European user base. MyHeritage DNA provides ethnicity estimates across 42 ethnicities and connects you with DNA matches worldwide. Their integrated family tree builder and historical photo enhancement tools add unique value.

One of the oldest genetic genealogy companies, founded in 2000. FamilyTreeDNA uniquely offers Y-DNA and mtDNA tests for deep paternal and maternal lineage tracing, alongside standard autosomal DNA testing. Their surname and geographical DNA projects are unmatched in the industry.

UK-based company offering exceptionally detailed regional breakdowns, especially within the British Isles (21 sub-regions). Living DNA combines ancestry analysis with wellbeing reports covering nutrition, fitness, and metabolism. Their data is kept in the EU under GDPR protections, enhancing privacy.

Offers 30x whole genome sequencing, capturing nearly 100% of your DNA versus the 0.02% that genotyping chips cover. Nebula provides regularly updated reports as new research emerges, and emphasizes data ownership with blockchain-based consent management. Ideal for those wanting the deepest genetic insights available.

European-based whole genome sequencing company providing 30x coverage. Dante Labs delivers a comprehensive health report, pharmacogenomic analysis, and ancestry composition. They also offer rare disease screening panels and nutrition-focused reports based on your full genetic data.

A marketplace-style platform offering both sequencing services and an app store for DNA analysis. Sequencing.com provides whole genome sequencing at 30x coverage and accepts raw data uploads from all major testing services. Users can purchase individual health, ancestry, or wellness reports through their marketplace.

Spanish company offering genotyping-based health and ancestry reports. TellmeGen covers over 400 conditions and traits including drug response, inherited conditions, and personal traits. Their platform is available in multiple languages and features a user-friendly dashboard for exploring results.

Hong Kong-based company offering whole exome sequencing, which covers all protein-coding regions of DNA. CircleDNA provides over 500 reports spanning health risks, cancer screening, pharmacogenetics, ancestry, and wellness. Their Premium kit includes diet and fitness recommendations based on genetic markers.

Combines ancestry and health reporting with a focus on user-friendly timelines. CRI Genetics uses a proprietary algorithm to deliver ancestry reports going back 50+ generations and health reports covering conditions, traits, and nutrition. Their dual-platform approach appeals to those wanting both deep ancestry and actionable health data.

Focuses primarily on health and wellness rather than ancestry. Vitagene accepts raw DNA data uploads from 23andMe, AncestryDNA, and other providers, then generates personalized supplement, diet, and exercise recommendations. Their action-oriented reports make genetic data practically useful for daily health decisions.

Now part of Labcorp, Invitae offers comprehensive genetic testing across cardiology, neurology, oncology, pediatrics, and reproductive health. Their tests are physician-ordered and most include genetic counseling. Invitae has tested over 4 million patients and offers one of the broadest clinical genetic testing menus available.

Specializes in cell-free DNA testing for oncology, women's health, and organ health. Natera's Signatera test is a pioneering personalized circulating tumor DNA assay used for cancer monitoring and recurrence detection. Their Panorama prenatal test is one of the most widely used NIPT tests in the United States.

Pioneer in liquid biopsy technology for advanced cancer patients. Guardant360 analyzes circulating tumor DNA from a simple blood draw to identify genomic alterations across 74 genes relevant to solid tumors. Their test is FDA-approved as a companion diagnostic and helps oncologists select targeted therapies.

Known for Cologuard, the non-invasive at-home colon cancer screening test. Exact Sciences also offers Oncotype DX, a genomic test that analyzes the activity of specific genes in breast, colon, and prostate tumors to predict recurrence risk and chemotherapy benefit. Their tests have been used by millions of patients.

A pioneer in hereditary cancer testing with over 25 years of experience. Myriad's myRisk panel assesses 48 genes associated with hereditary cancers including breast, ovarian, colorectal, and prostate. Their BRACAnalysis test was the first commercial test for BRCA1/2 mutations and remains widely used today.

A clinical lab specializing in hereditary disease testing. Ambry offers panels for cancer, cardiovascular conditions, neurological disorders, and rare diseases. They are known for rigorous variant interpretation and comprehensive gene coverage. Their patient assistance program helps make testing accessible to those with financial need.

A leading provider of exome and genome sequencing for rare disease diagnosis. GeneDx has analyzed over 500,000 clinical exomes and identified causative variants in thousands of previously undiagnosed cases. They focus on pediatric and adult rare disease, offering both whole exome and whole genome sequencing ordered by specialists.

Bridges the gap between DTC and clinical testing with physician-ordered genetic tests for hereditary cancer and heart conditions. Color includes genetic counseling with every test and focuses on actionable genes with established clinical guidelines. They serve both individual consumers and large employer health programs.

An AI-driven precision medicine company that combines genomic sequencing with clinical data analysis. Tempus offers broad tumor sequencing panels and has built one of the largest libraries of clinical and molecular data. Their platform helps oncologists make data-driven treatment decisions using both DNA and RNA sequencing.

A Roche company offering comprehensive genomic profiling of solid tumors and hematologic malignancies. FoundationOne CDx is FDA-approved and analyzes 324 genes, tumor mutational burden, and microsatellite instability. Their reports match detected alterations to FDA-approved therapies and clinical trials.

One of the largest clinical laboratory networks in the United States, Quest offers a broad menu of genetic tests including hereditary cancer panels, cardiovascular genetics, and prenatal screening. With over 2,000 patient service centers nationwide, Quest provides convenient sample collection and rapid result delivery through their patient portal.

A global life sciences company offering genetic testing through their extensive laboratory network. Following their acquisition of Invitae, Labcorp's genetic testing portfolio expanded dramatically. They offer hereditary cancer testing, pharmacogenetics, prenatal screening, and now DTC options through their consumer-facing OnDemand platform.

The most widely used pharmacogenetic test for mental health medications. GeneSight analyzes 12 genes to predict response to 57+ FDA-approved psychiatric medications including antidepressants, antipsychotics, and mood stabilizers. Results categorize medications into green (use as directed), yellow (use with caution), and red (increased risk) bins for clinical guidance.

Offers the Professional PGx Express test covering 24 genes across 130+ medications. Genomind distinguishes itself by including the MTHFR gene (involved in folate metabolism and antidepressant response) and SLC6A4 (serotonin transporter) alongside standard pharmacogenetic markers. Their reports include detailed clinical annotations for prescribing physicians.

The only NIPT that distinguishes between maternal and fetal DNA using SNP-based technology. Panorama screens for trisomies 21, 18, and 13, sex chromosome aneuploidies, and triploidy. It also offers microdeletion screening for five clinically relevant syndromes including 22q11.2 (DiGeorge syndrome).

Offers the Foresight carrier screening panel covering 558+ conditions including cystic fibrosis, spinal muscular atrophy, and fragile X syndrome. Myriad's Prequel prenatal screen uses cell-free DNA to assess fetal risk for common chromosomal conditions. Both tests are physician-ordered and supported by genetic counselors.